Have you been diagnosed with an ophthalmic disease?
The eye is an “immune-privileged” site where foreign antigens can be tolerated without producing an immune response. Due to the fact that the retina of the eye is easily accessible for treatment and being the eye a closed space the stem cell therapy could have the perfect conditions for the stem cell surviving, replicating, and performing their function.
ICELLI has used cellular therapies for the following conditions of the ophthalmic disease:
OPHTHALMIC (EYE) DISEASE
OVERVIEW – The eye is an “immune-privileged” site great for the immuno-modulatory work of the stem cells
Retinopathies involve the disease of the retina, the light-sensitive tissue at the back of the eye necessary for good vision. Maculopathies involve the disease of the macula, the part of the eye where sharp, straight-ahead vision occurs. Many research studies show that adult stem cells from bone marrow and adipose tissues can repair a damaged retina or a damaged macula.
OPHYHALMIC DISEASE SAMPLE – Diabetic Retinopathy (DR)
Diabetic retinopathy is a disease caused by changes in the blood vessels of the retina of the eye and it is the most common diabetic eye disease and a leading cause of blindness in American adults.
How is Diabetic Retinopathy working against you?
In some people with diabetic retinopathy, blood vessels may swell and leak fluid swelling the macula (macular edema) with possible blurred vision. In other people, abnormal new ad fragile blood vessels grow on the surface of the retina and leak blood into the center of the eye causing blurring vision or block ink vision.
How can stem cell therapy work for you?
Once injected within the intraocular fluid, the stem cells migrate to the damaged retina and integrate within the retinal tissue so they could regenerate photoreceptors or stimulate them to function by secreting growth factors that regenerate the damaged neural cells. The stem cells can eventually replace damaged cells with healthy ones generated from in-itself, through the effects of the stem cells in maintaining a healthy tissue microenvironment, or by attracting endogenous-circulating progenitor cells to help repair damaged cells in the eye. Effectiveness of the treatment depends greatly on the stage of the condition at the time of treatment. Some patients may require more than one treatment to potentially regenerate a tissue that has been damaged for years.
TREATMENT: ISCELLI’S protocol for use of adult stem cell therapy on vision loss conditions starts with an initial ophthalmoscopic exam of the retina and general evaluation of the eyes done by an ISCELLI’S ophthalmologist hours before the cells transplant. This evaluation will confirm the basic diagnosis presented by the patient and current status of visual acuity, pupil function, ocular motility, visual field, and intraocular pressure.
The transplant of stem cells is done as an intravitreal (inside the eye) or retrofundal (behind the eye) local injection of primary (fresh) stromal/stem cells or culture expanded mesenchymal stem cell. The intravitreal route facilitates immediate access to the inside of the eye with minimal complications. The procedure is performed at our clinics, takes less than one hour and carries minimal risks when done properly.
Diabetic patients with uncontrolled diabetes or with more than 10 years with the disease may be required to go through special protocols under our supervision to maintain blood glucose levels within normal range around the time of the procedure or may not even qualified for these procedures.
Are you living with an ophthalmic disease?
If you’ve been diagnosed with an advanced ophthalmic disease you may be able to improve your quality of life through stem cell treatments. In patients with diabetic retinopathy no treatment may be needed, unless macular edema occurs. People with proliferative retinopathy can reduce their risk of blindness by 95% with timely treatment and appropriate follow-up care. Otherwise, proliferative retinopathy is treated with laser surgery, and in case of severe bleeding, eye surgery (vitrectomy) can be needed.
If you would like to find out more about our available treatment options,
please contact one of our patient care coordinators today
at 954-874-9900 to schedule a free consultation.