LEVEL 2 PROCESS– Minimal Processing. A level 2 is defined as one in which stem cells are in fact extracted from a sample of fat cells usually taken from the patient’s abdomen. These extracted cell are “stromal vascular fraction (SVF)” or sample containing different types of nucleated cells, among them, a small percentage are in fact stem cell.
These stem cells are not expanded or multiplied a posteriori in the lab but they are generally conditioned with various growth factors to activate the cells before the immediate application to the patient. Example of this level 2 of stem cell therapy is the by which fat cells are obtained by a minilipo, an SVF is isolated in the office and combined with PRP, a growth factor, or a laser. before its application or transplant.
- This is the level of therapy practiced almost universally by any medical provider or physician limiting his/her cellular therapy to the US territory Level.
LEVEL 3 PROCESS– Culture Expansion. Level 3 represents the most advanced and complex approach to stem cell therapy for which specialized experience and a sophisticated and expensive laboratory is required. Level 3 is defined by the use of advanced cell culture techniques to expand cell numbers for yield of adipose-derived mesenchymal type stem cells (AMSCs). Only under this level of cell processing, stem cells can be expanded up to a requested number.
ISCELLI is one of the very few private company providing stem cells at level three.